Around this time last year, my Husband and I were preparing to get pregnant. We already had to come to terms that we would have a difficult pregnancy after losing 2 pregnancies in 2019 and having been diagnosed with a reproductive immune disorder, APAS.

Around this time last year, my Husband and I were preparing to get pregnant. We already had to come to terms that we would have a difficult pregnancy after losing two pregnancies in 2019 and having been diagnosed with a reproductive immune disorder, APAS.

APAS is one of the five Reproductive Immune Disorders and the most common abnormal immune system problem. For women trying to conceive, it can prevent implantation thus preventing pregnancy in the first place and may also prevent the pregnancy to progress causing miscarriage and fetal death. When I went to Bloodworks Katipunan to have run the diagnostic tests requested by my Immunologist, Dra. Lara Aleta, I was hoping for the best and not have APAS or any other RID’s, but  I was not spared.

In November 2020, we found out that I have APAS, RID Category 2, was also positive for RID Category 1 and Vitamin D deficient.

READ: About APAS | How We Found Out I Have It

As soon as we found out the diagnosis, we had a quick step back to swallow all the information in and to mentally prepare ourselves for the battle ahead. And boy was it a battle indeed. It was in the middle of the pandemic and treating APAS so we get clearance to TTC was difficult. We had to do online consultations with our doctors and went to the clinic for tests and treatments only. Building the medical team relationship and trust via online interaction was hard but it must be done.

Treatment we had to go through

We started our treatment the week after we found out about the diagnosis. My husband became my donor and after getting him cleared for blood donation, we started treatment. My treatment was LIT, Lymphocyte Immunization Treatment, to increase my antibodies to block/stop my immune system from attacking the pregnancy. A blood sample is taken from my husband every treatment. The sample is then processed in the lab on the same day with the white blood components left. It is then injected in my arm, subcutaneously (under skin). To my understanding, it slowly allows the my body to get used to and identify my husband’s blood components as, somewhat, my own. The treatment is done every three weeks until my LAT, Lymphocytes Antibody Test, scores reached the level safe for pregnancy.

Prior to treatment, my Immunologist told us that we have to increase my LAT scores before trying to get pregnant. It took us four LIT sessions before we were reached LAT scores that was safe for me to get pregnant and was cleared to try to conceive. 

Medications we took prior to getting pregnant

Before we started APAs treatment, we went to see my OB-Perinatologist to inform her the diagnosis and asked if there were any additional management she wanted us to do. She told me to continue taking my prenatal vitamins and folic acid. She also added to she her as soon as I get pregnant or suspect that I am. And to see her if if we are unable to get pregnant when given a go signal to TTC by the Immunologist.

Our Immunologist prescribed us to take CoQ10 on top of our multivitamins and other supplements. She did not prescribe probiotics, she encouraged me to increase my probiotics with Yakult drink and to be mindful of what I eat. Before getting pregnant, I was taking prenatal meds, Folic Acid, Vitamin D, Vitamin C + zinc and CoQ10. I would take this religiously spread throughout the day.

Lifestyle  before and during APAS treatment

Before we decided to start with APAS treatment, my husband and I were already decided that we will try to get pregnant again. Like other pregnancies, we took a healthier approach prior to TTC. On the third pregnancy, we exercised by doing daily walks of 1-2H a day. We would hit 10,000 steps or more each day. This not only gave us a fit body but also helped us lose weight. We also lessened caffeine and sugar intake by taking out the foods and drinks we usually go for. It was also important for us to go to bed early. We did this so we can have longer sleep time and be well-rested. On my case, I lessen my work hours by dropping my second client. So instead of working full-time, I was only working four hours a day with a healthy working environment.

Knowing my body cues and ovulation period

I also took this time to know more about my body. I would take notes on what I would feel and how my body is during ovulation, PMS and my period. I tracked my menstrual cycle using an app to help us identify my ovulation phase more accurately. Before the treatment, I already my my cycle and can identify when I ovulate using the app and also the ovulation symptoms from my body.

Mental and emotional preparation

Reading through other women’s experiences on a support group for APAS women on Facebook, I could only imagine the mental and emotional battle one goes through. So my husband & I researched and read about the experiences of other couples to gauge how it would be for us. We knew that the treatment was not an assurance of successful pregnancy and that we’d have a challenging pregnancy if the treatment is successful. Either way, we knew that it would be a mental and emotional battle for us. Preparing and psyching oneself helps navigate us better deal and navigate through the rough paths. So when we did get pregnant and I was told to stay in bed for most of my first and second trimester, I was in a much better position to accept the pregnancy difficulty.

When we were given the go signal to try to conceive, it was easier for us to identify my ovulation period. My body was also fairly healthier and more fit to withstand the months of lying down mostly in bed. The vitamins and supplements I took also helped boost my immune system with no flu or even threat of flu in the whole duration of the pregnancy. There was mental and emotional struggle still but it was not going-crazy kind of way. I have learned to focus my energy in prayer when the rough times hit. It was a way for me to surrender myself, my body, the pregnancy and the baby to our Almighty Lord for everything else is beyond my hands and control.

There are a lot of things one can do to better their chance at getting pregnant. It is best though to seek professional help with your medical team if you are having a hard time getting pregnant or having a difficult pregnancy. we can only do so much from our own strength, research and resources but your medical team are equipped to handle and give you sound advise fit for your case.